In this role, you will establish and drive BioArctic’s growing initiative within oligonucleotide therapeutics. You will be our internal expert in the field, participating in drug development programs and contributing both strategically and scientifically.
This is a dynamic role that combines concept development with the coordination of internal and external activities, as well as hands-on data analysis and documentation. Depending on the candidate, experimental work may also be required. The focus is on the design, analysis, and evaluation of therapeutic oligonucleotides, as well as integrating these technologies into BioArctic’s research portfolio. You will work in cross-functional project teams and collaborate closely with external CROs.
The position is based in Stockholm, full-time, open-ended, with BioArctic as the employer.
**Key Responsibilities**
- Participate in drug development programs, driving scientific strategy and execution.
- Lead and perform design and analyses of oligonucleotides such as ASO and siRNA using bioinformatic tools.
- Participate in the development of conjugation strategies (e.g., linker, peptide, ASO–antibody conjugates) and detailed characterization.
- Assess gene expression (qPCR, NGS) and cell- and tissue-based analyses. Evaluate target and off-target effects.
- Plan, coordinate, and follow up on work performed by external CROs.
- Contribute to project strategies and cross-functional scientific discussions.
**Qualifications**
- Ph.D. in molecular biology, molecular genetics, biochemistry, pharmacology, or a related field.
- Deep understanding of ASO and siRNA technologies.
- Proven experience in oligonucleotide design and bioinformatic analysis.
- Experience in analyzing ASO or siRNA effects in cell- and tissue-based assays (on-target and off-target).
- Solid understanding of gene expression analysis (qPCR, NGS).
- Experience from the biotech or pharmaceutical industry, including sponsorship of CROs or equivalent.
- Excellent communication skills in English.
**Meriting Qualifications**
- In vivo experience with ASO or siRNA.
- Familiarity with research on brain disorders.
- Experience in conjugation chemistry, especially ASO–antibody conjugates.
- Swedish language skills.
**Who You Are**
- Analytical and solution-oriented.
- Communicative and confident in a leading scientific role.
- Proactive and independent, yet collaborative.
- Structured and detail-conscious without losing momentum.
**Application**
Apply as soon as possible – interviews are held continuously. For questions about the role, please contact Anna Rennermalm, Search4S,
[email protected], +46 70 794 20 05.
Last application date: Dec 14th, 2025.
**About BioArctic**
BioArctic is an innovative Swedish biopharma company focused on neurodegenerative disease research, such as Alzheimer’s disease, Parkinson’s disease, and ALS. BioArctic’s research has resulted in the world’s first fully approved disease-modifying drug against Alzheimer’s disease. The company has also developed the BrainTransporter technology, which has the potential to improve treatment outcomes for brain diseases. BioArctic’s head office is located in Stockholm, Sweden, and the company has more than 130 employees.
Learn more about the company at www.bioarctic.com.