Postdoctoral Researcher in Experimental Biomedical Research

Umeå University is one of Sweden's largest higher education institutions with over 37,000 students and approximately 4,700 employees. The university offers a diverse range of high-quality education and world-leading research across multiple scientific disciplines, and is home to the groundbreaking discovery of the CRISPR-Cas9 gene scissor, which was awarded the Nobel Prize in Chemistry. At Umeå University, everything is close. Our compact campus makes it easy to meet, collaborate, and exchange knowledge, which fosters a dynamic and open culture. The societal transformation and major green investments we see in northern Sweden create enormous opportunities and complex challenges. For Umeå University, this means conducting research about – and in the midst of – a society in transformation. It also means delivering educational programs for regions that need to expand quickly and sustainably. This is simply where the future is created. Interested in learning more? https://www.umu.se/jobba-hos-oss/om-universitetet-som-arbetsplats/ The Faculty of Medicine is one of the largest faculties at Umeå University and attracts many students with a comprehensive range of educational programs in medicine, dentistry, health, and care. We offer a well-developed research infrastructure and an inspiring, dynamic environment with leading research. Our close collaboration with the four regions in the Northern Healthcare Region is seen as a significant mutual asset for developing research and education and ensuring the availability of our future healthcare personnel. "At the Department of Community Medicine and Rehabilitation, we conduct research and teaching within our five subject areas: Occupational Therapy, Physiotherapy, Geriatrics, Sports Medicine, and Rehabilitation Medicine." Project Description The Department of Community Medicine and Rehabilitation is seeking a postdoctoral researcher for the "COPD-HIT" project, an international multi-center project aimed at developing and validating an in-vitro loading model against in-vivo blood and muscle adaptations (biopsies) from individuals with Chronic Obstructive Pulmonary Disease (COPD) and matched healthy controls who have undergone physical training at various intensities and durations. Job Responsibilities As a postdoctoral researcher in the project, you will combine experimental studies with analysis of in-vivo blood and muscle data. Since the project is translational, you will collaborate with clinical researchers, preclinical researchers, and professionals from other research fields. You will have a central role in the project and work independently on: - Establishment and cultivation of primary human muscle cells, including isolation, culture, and differentiation. - In vitro models for mechanical loading of muscle cells, particularly using the FlexCell system - Omics techniques, including sample preparation for proteomics and analysis and interpretation of generated data. - Protein analyses, with particular experience in techniques such as Western blot and ELISA. - Gene expression analysis, including quantitative PCR (qPCR) for mRNA analysis. - Immunohistochemistry and immunocytochemistry, including tissue preparation, sectioning, and staining. - Microscopy techniques, focusing on confocal microscopy and image analysis. - Contributing to study design, selection of analytical methods, and method development. - Visual presentation of analyses and results and writing scientific publications. - Collaboration with clinical researchers, bioinformaticians, and other experts in the project group. Qualifications Eligible for employment as a postdoctoral researcher is someone who has completed a doctoral degree, or a foreign degree deemed equivalent to a doctoral degree, in life sciences or another equivalent field. This eligibility requirement must be met by the time the employment decision is made. Preference will be given to those who have obtained their degree within the last three years. To be considered for the position, you must have: - Documented experience working with the FlexCell tension system is particularly meritorious. - A strong background in molecular biology/biomedicine and/or biotechnology, especially extensive experience in molecular/biochemical laboratory techniques and familiarity with cell culture and preferably three-dimensional cell culture models. - Proficiency in scientific English and good general communication skills in English (both verbally and in writing) is expected. More About the Position This is a full-time, fixed-term employment for two years according to the postdoctoral employment agreement. Application Apply through our recruitment system Varbi. Your application should include: - A brief description of research interests and motivation for why you are interested in the position. - CV - Publication list - Doctoral degree certificate