The University of Gothenburg meets societal challenges with diverse knowledge. With 58,000 students and 6,800 employees, the university is a large and inspiring workplace. Strong research and attractive educational programs attract researchers and students from around the world. With new knowledge and perspectives, the University of Gothenburg contributes to a better future. The Department of Odontology provides education for dentists, dental hygienists, and dental technicians at both undergraduate and advanced levels. All educational programs lead to a professional degree as well as a general degree. The department also conducts research and doctoral education in dental science, along with continuing education activities. The department collaborates with Public Dental Service Västra Götaland in the clinical part of the undergraduate education and in clinical research.
The activities at the Department of Oral Biochemistry are conducted in a research laboratory with projects focusing on omics-based characterization of human soft tissues affected by peri-implantitis, a common condition in dentistry that impacts the tissues around dental implants and is characterized by bone loss and inflammation in the surrounding soft tissue.
Omics is a collective term for comprehensive methods for large-scale analysis of biological molecules such as DNA, RNA, proteins, and epigenetic markers. These methods are often performed using Next-Generation Sequencing (NGS) and provide a holistic view of the molecular processes contributing to disease development. In this project, for example, epigenomics (for genome-wide DNA methylation analysis) and transcriptomics (for analysis of the entire RNA content) are utilized.
DNA methylation is a central epigenetic mechanism that regulates gene expression without altering the DNA sequence and is believed to play an important role in the pathogenesis of peri-implantitis. Genome-wide DNA methylation analysis allows for the evaluation of DNA methylation across the entire genome, while transcriptomics complements the analysis by highlighting the functional consequences of DNA methylation, that is, how DNA methylation affects RNA levels in the tissues and thus gene expression. Together, genome-wide DNA methylation analysis and transcriptomics will provide a more comprehensive understanding of the molecular mechanisms underlying the pathogenesis of peri-implantitis and may contribute to the development of improved treatment strategies.
Job Responsibilities
This position offers the opportunity to participate in research projects expected to result in several publications and conference presentations, as well as to work in an academic research environment with modern techniques in molecular biology.
Daily tasks include planning and performing laboratory work in molecular biology and handling human tissue samples. Examples of tasks include:
• Extraction of DNA and RNA from human soft tissue samples and analysis of their quality and quantity.
• Library preparation of DNA (for genome-wide DNA methylation analysis) and RNA (for transcriptomic studies) in preparation for Next-Generation Sequencing (NGS) conducted at Core Facilities.
Experience in adapting laboratory protocols to different sample types, as well as experience in library preparation and working with DNA/RNA, is advantageous.
Qualifications
You should have a degree as a biomedical analyst with an interest in and experience in molecular biology, cell biology, or another relevant field for the position. You should have an understanding of laboratory work in research within an academic environment. Great emphasis will be placed on personal suitability and the ability to work independently as well as in a team.
Employment
The position is temporary for 11 months, with a 50% workload, located at Section 2, Department of Odontology, Sahlgrenska Academy. The appointment will be made as soon as possible by agreement.
Contact Information for the Position
For further information about the position, please contact Farah Asaad, Associate Professor and University Lecturer. Phone: 076-618 31 98. Email:
[email protected].
Trade Unions
Union representatives at the University of Gothenburg can be found here: http://www.gu.se/omuniversitetet/aktuellt/lediga-jobb/fackliga-kontaktpersoner
Application
You apply for the position via the University of Gothenburg's recruitment portal by clicking the "Apply" button. As an applicant, you are responsible for ensuring that your application is complete according to the advertisement and that it reaches the university no later than the application deadline.
A copy of your certification as a biomedical analyst must be attached to the application.
Application deadline: 2025-12-08.
The university actively works for a work environment with equal conditions and values the qualities that diversity brings to the organization.
The university applies individual salary setting.
According to the National Archives' regulations, the university is obliged to store application documents for two years after the appointment decision. If you, as an applicant for a position, specifically request the return of your documents, they will be sent back after the two years have passed; otherwise, they will be disposed of.
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